Igennus Super B-Complex Methylated B Vitamins, Sustained Release, Clean Label, MTHFR Supplement with Methylfolate & B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets

I am compound heterozygous (MTHFR ). Which is normally not a huge deal, but I also have a history of stroke and autoimmune activity as well as activated Epstein-Barr virus. It becomes a little more important to get the right B complex.If you are experiencing non-stop fatigue and cannot figure out why definitely ask your doctor about Epstein-Barr virus and getting tested along with having a test for MTHFR. I exhausted the other options and finally may have my answer. It seems that Covid may have reactivated my Epstein-Barr virus, which should remain dormant after having mono when I was a teenager 30 years ago.I was going to go with a different company until I realized that they had a different form of B6 then was ideal for someone with MTHFR.This brand has the form I wanted. Here is why:Confirm B6 FormIf the label just says “Pyridoxine” or “Vitamin B6” without specifying P-5-P, then it’s likely the inactive form (pyridoxine HCl).• Some people with MTHFR (or impaired liver detox) don’t convert pyridoxine well.• Look for P-5-P (pyridoxal-5-phosphate) — it’s gentler, active, and more effective for reducing homocysteine.Watch for Niacin Form & Dose• If it contains nicotinic acid, high doses can use up methyl groups and cause “niacin flush”• If it’s niacinamide or in small amounts, it’s usually fine• You don’t have to avoid it — just good to be aware, especially if you ever feel flushed or tired after taking it👀 this brand has the no flush niacin😁If you are positive for MTHFR be sure to research these things. I was pleased to find that this is a good choice.I have just started taking it for a couple of weeks. It is yellow of course I do not chew it so I do not know what the taste is, but it is fairly quick and I just take two at a time. It does say you can take them at two separate times. Quick and easy great choices.Using the proper forms of B vitamins—especially 5-MTHF (methylfolate)—is essential for people with MTHFR mutations because their bodies can’t efficiently convert synthetic folic acid into the active form needed for methylation. Taking methylated forms (like 5-MTHF and methylcobalamin) bypasses the genetic bottleneck, allowing the body to process nutrients, detoxify properly, and regulate homocysteine levels more effectively.📝I will update in a couple of months to see what results I get.

Try methylated b complex, please! In 2 months I have noticed improvements in many areas. My energy and motivation! My mood, I'm less irritable & anxious. I have less neuropothy in my hands and feet. My skin is softer and glowy. My memory is sharper. I have also changed to eating only whole foods. I walk for exercise now and take methylated b complex. I feel great! Antacids, aging, other medications and mthfr can block how we absorb our b vitamins and a deficiency can occur. B vitamins are water soulable and the body will excrete excess through the urine. B12 is stored in the liver to prevent a deficiency. Stores of b 12 can become depleted through infection, child birth, surgery etc. if you are not eating whole foods and supplementing with methylated b12. I noticed improvements the first day I started taking these! Good luck, I hope you see improvements to your health and quality of life. Take care!

Seems to work well for me. But...if you google interactions with b vitamins the first thing that comes up is that vit c might not be ideal to mix with b12. So why they add vit c to these vitamins is anyone's guess. Best to just take them and see how you feel and forget what the internet has to say about it 🤷

a decent well rounded VIT B supplement.

Came timely and works great. Noticeable effects on taking it the first time.

Really like these I have more energy

I'm pretty sure this is the best B-vitamin I have ever taken. My feet started itching- did you know that's a sign of a B-12 deficiency? Anyway, I've always known I need the methyl forms of B-12 and B-6 and I wanted a sublingual, but I liked the reviews of this one so decided to give it a shot. I actually take it like a sublingual (it's gross, though) and let me tell you, the effect is immediate! I can feel my eyes getting clearer and a boost in my energy and mood. It's incredible.

Unfortunately did not agree with me. First time with methylated folate and I think that was what gave me terrible fatigue and perhaps the sour stomach. I know methylated vitamins are great for some people so not blaming the maker. Just was not for me! Everything else in the capsule was something I’ve had before with no problem, even the methylcobalamin.